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USB was a great leap forward. Its convenience, flexibility, and interoperability have simplified everything from cabling to device installation. But as good as it is, USB was designed with safe office and IT environments in mind. When it moves out into the real world, as it is currently doing in industries ranging from manufacturing to health care, USB reveals a number of inherent weaknesses, like a proclivity for ground loops. You can take steps to make USB safe and reliable in harsh environments.